Clomid (otherwise known as Clomiphene Citrate or Serophene) is a treatment for female infertility. It was formulated originally to treat a condition known as anovulation, which simply describes the lack of regular ovulation.
In regular ovulation, eggs live inside of ovarian follicles until ovulation, when it is released. Specifically, the follicle grows in size during the regular 28 day menstrual cycle, and then ruptures near the end and releases the egg, which is then supposed to be picked up by the fallopian tube, where it should meet with sperm and become fertilized. For a variety of reasons, such as polycystic ovarian syndrome (PCOS), this regular cycle may not occur. Clomid works by blocking the hormone oestrogen from affecting your body, which in turn causes the production of two other hormones–follicle-stimulating hormone (FSH) and luteinising hormone (LH)–which act to increase the effect of ovulation (follicle-stimulating hormone causes eggs to ripen and ready for release, and luteinising hormone triggers the rupturing process in the follicles, thereby releasing the eggs into the fallopian tube).
Clomiphene Citrate has been in the market for more than 50 years, and it has been consistently proven safe. It was initially introduced in 1967 in the United States, where it underwent approval by the Food and Drug Administration, which is a governmental regulatory body which approves the entry of food and medications into the market. It has subsequently been approved three more times–once in 1982, then again in 1988, and most recently in 1999.
Clomiphene Citrate should not be used if a patient has an allergy to any component compounds, or if they have abnormal vaginal bleeding, an ovarian cyst not related to polycystic ovarian syndrome (PCOS), any history of liver disease or issues with the pituitary gland, or if they are already pregnant. Additionally, if a patient has been diagnosed with either endometriosis or uterine fibroids, they should consult a physician before starting this medication, as it may cause complications with those two disorders specifically.
Clomiphene Citrate should be taken in the initial first few days of a patient’s menstrual cycle, and then taken consecutively for five days after. Ovulation typically occurs within 5 to 10 days of the first dose–to improve your chances of conceiving while ovulating, it is generally recommended to have sexual intercourse during ovulation.
In Australia, a shortage of this compound is currently underway. According to the Therapeutic Goods Administration, a manufacturing shortage will cause difficulty when searching for this product. This should be resolved by the beginning of July, 2017–until then, a french imported product, Clomid (Clomiphene Citrate), has been approved as an alternative medication. Despite this shortage, it is still possible to receive either Clomid (the domestic version, known as Clomiphene Citrate or Serophene) either online or through pharmacies. A physician’s prescription may be required before you receive this medication, but regardless, speak to your physician before beginning or stopping this medication.
Depending on the dosage preferred (Clomid ranges from 25mg to 100mg), this medication or its generic equivalent can be found relatively easily online; they range from AU$1 to AU$2 per pill. Keep in mind that buying in bulk will save you money–large orders will usually be cheaper.